Trade Name: Imbruvica™

Ibrutinib is the generic name for the trade drug Imbruvica™. In some cases, health care professionals may use the trade name Imbruvica™ when referring to the generic drug name ibrutinib.

Drug Type:

Ibrutinib is a targeted therapy. Ibrutinib inhibits the function of Bruton's tyrosine kinase (BTK). (For more detail, see "How this drug works," below.)

What Ibrutinib Is Used For

• Chronic graft-versus-host (cGVHD) disease after failure of one or more prior lines of systemic therapy.
• Chronic lymphocytic leukemia (CLL) who have received at least one prior therapy.
• Mantle cell lymphoma (MCL) who have received at least one prior therapy.
• Marginal zone lymphoma (MZL) who require systemic therapy and have received at least one prior anti-CD20-based therapy.
• Waldenstrom's macroglobulinemia.